Jorgensen Michael G, Slots Jørgen
University of Southern California School of Dentistry, Los Angeles 90089-0641, USA.
J Calif Dent Assoc. 2002 Apr;30(4):297-305.
A multifaceted antimicrobial approach is necessary for the successful management of destructive periodontal disease. Effective antimicrobial periodontal therapy aims to overwhelm periodontal pathogens with aggressive initial therapy and prevent previously suppressed pathogens from rising up anew through daily oral hygiene measures and frequent professional cleaning. Current antimicrobial periodontal therapy employs mechanical debridement performed with and without surgery, antibiotics, and antiseptics. Subgingival irrigation with povidone-iodine at the dentist's office and subgingival irrigation with dilute sodium hypochlorite for home-care constitute effective, safe, and affordable periodontal antimicrobial therapy. This article describes theoretical and practical guidelines for implementing rational and cost-effective antimicrobial principles in the management of periodontal disease.
对于破坏性牙周疾病的成功治疗，需要采取多方面的抗菌方法。有效的抗菌牙周治疗旨在通过积极的初始治疗压制牙周病原体，并通过日常口腔卫生措施和频繁的专业清洁，防止先前被抑制的病原体再次滋生。目前的抗菌牙周治疗采用有或无手术的机械清创、抗生素和防腐剂。在牙医诊所使用聚维酮碘进行龈下冲洗，以及在家护理时使用稀释的次氯酸钠进行龈下冲洗，构成了有效、安全且经济实惠的牙周抗菌治疗。本文介绍了在牙周疾病治疗中实施合理且具成本效益的抗菌原则的理论和实践指南。
