Raĭnova L V, Guseĭnova T G
Arkh Patol. 1975;37(4):49-55.
Biopsy specimens of the gum of patients with systemic lupus erythematodes, rheumatoid arthritis, and systemic sclerodermia, complicated or not with chronic odontogenous infection, and of 10 those of practically healthy persons with chronic odontogenous infection were studied. In patients with collagenous diseases outside the odontogenous infection foci there were observed considerable lesions of the microcirculatory bed vessels, largely of inflammatory nature.--productive vasculitis of the epithelium and connective tissue of the mucosa proper of the gum. The immunopathological character of the above-mentioned lesions in some cases was confirmed by the immunofluorescent method of investigation. The observed changes in vessels and the connective tissue of the gum in collagenous diseases reflected a locally generalized vasopathy of immune character and systemic disorganization of the connective tissue. Studies of gum biopsy materials in patients with collagenous diseases taken from chronic odontogenous infection foci revealed inflammatory changes in the gum tissues much more serious than in practically healthy people in analogous foci od odontogenous infection. Lesions of the gum in patients with collagenous diseases, not complicated with odontogenous infection, represented a background which aggravated the effect of this infection on the gum.
对患有系统性红斑狼疮、类风湿性关节炎和系统性硬皮病的患者的牙龈活检标本进行了研究，这些患者伴有或不伴有慢性牙源性感染，还研究了10名患有慢性牙源性感染的实际健康人的牙龈活检标本。在牙源性感染灶以外的胶原性疾病患者中，观察到微循环床血管有相当程度的病变，主要是炎症性质的病变——牙龈固有黏膜上皮和结缔组织的增殖性血管炎。上述病变在某些情况下的免疫病理特征通过免疫荧光研究方法得到了证实。在胶原性疾病中观察到的牙龈血管和结缔组织的变化反映了具有免疫特征的局部全身性血管病以及结缔组织的系统性紊乱。对取自慢性牙源性感染灶的胶原性疾病患者的牙龈活检材料进行研究发现，牙龈组织中的炎症变化比在类似牙源性感染灶的实际健康人更为严重。未伴有牙源性感染的胶原性疾病患者的牙龈病变是加重这种感染对牙龈影响的一个背景因素。
