Jothy S, Bilodeau J L, Champsaur H, Simpkins H
Biochem J. 1975 Jul;150(1):133-5. doi: 10.1042/bj1500133.
It is shown that tri-iodothyronine injected intravenously into thyroidectomized rats induces an early and transient activation of rat liver RNA polymerase II which could be demonstrated to occur 40-80 min after hormonal treatment. There was a simultaneous increase in the concentration of acidic proteins bound to chromatin.
结果表明,向甲状腺切除的大鼠静脉注射三碘甲状腺原氨酸会诱导大鼠肝脏RNA聚合酶II早期短暂激活,这可证明在激素处理后40 - 80分钟发生。与染色质结合的酸性蛋白浓度同时增加。