Görich Johannes, Krämer Stefan, Tomczak Reinhard, Seifarth Harald, Merkle Elmar, Sunder-Plassmann Ludger, Orend Karl-Heinz, Ashquan Yahia, Pamler Reinhard
Department of Radiology, University of Ulm, Germany.
J Endovasc Ther. 2002 Apr;9(2):180-4. doi: 10.1177/152660280200900207.
To evaluate the frequency and significance of thromboembolic complications following endovascular treatment of aortic aneurysms.
One hundred seventy-four patients (153 men; mean 71.4 years, range 26-90) underwent endovascular repair of aneurysms of the thoracic (n = 38) or abdominal (n = 136) aorta using a variety of endografts. All patients were examined preprocedurally using 3-phase helical computed tomography (CT) to determine appropriate endograft size. To exclude the occurrence of infarction in parenchymal organs, the first postprocedural CT scan was compared with preoperative findings. Newly recognized perfusion deficits were taken as evidence of procedure-related infarction.
Infarctions were detected in 16 (9.2%) patients: 13 in the kidneys, 2 in the spleen, with 1 in the mesentery; only the mesenteric infarction was clinically symptomatic. Both splenic infarctions were associated with deployment of stent-grafts in the thoracic aorta (5.3% of the 38 patients), while the mesenteric and 13 renal infarctions were seen in patients with infrarenal abdominal aortic aneurysms (0.7% and 9.6%, respectively, of 136 patients). One patient experienced complete thromboembolic occlusion of a renal artery, which was partially recanalized with intraoperative lysis.
Thromboembolic complications of endovascular aortic aneurysm repairs are not uncommon, and although usually asymptomatic, these sequelae have the potential to be life threatening. Perfusion abnormalities may respond to immediate lytic therapy with complete dissolution of the thrombus in certain isolated cases.
评估主动脉瘤血管内治疗后血栓栓塞并发症的发生率及意义。
174例患者(153例男性;平均年龄71.4岁,范围26 - 90岁)接受了胸主动脉(n = 38)或腹主动脉(n = 136)瘤的血管内修复,使用了多种血管内移植物。所有患者在术前均采用三期螺旋计算机断层扫描(CT)检查以确定合适的血管内移植物尺寸。为排除实质器官梗死的发生,将术后首次CT扫描结果与术前结果进行比较。新发现的灌注缺损被视为与手术相关梗死的证据。
在16例(9.2%)患者中检测到梗死:13例发生在肾脏,2例在脾脏,1例在肠系膜;只有肠系膜梗死有临床症状。2例脾脏梗死均与胸主动脉内支架移植物的植入有关(38例患者中的5.3%),而肠系膜梗死和13例肾梗死见于肾下腹主动脉瘤患者(分别为136例患者中的0.7%和9.6%)。1例患者出现肾动脉完全血栓栓塞性闭塞,术中溶栓部分再通。
血管内主动脉瘤修复的血栓栓塞并发症并不少见,尽管通常无症状,但这些后遗症有可能危及生命。在某些孤立病例中,灌注异常可能对立即溶栓治疗有反应,血栓可完全溶解。