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真核寄生虫刚地弓形虫中的分泌运输:少即是多。

Secretory traffic in the eukaryotic parasite Toxoplasma gondii: less is more.

作者信息

Joiner Keith A, Roos David S

机构信息

Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT 06520, USA.

出版信息

J Cell Biol. 2002 May 13;157(4):557-63. doi: 10.1083/jcb.200112144.

Abstract

Name a single-celled eukaryote that boasts a small genome size, is easily cultivated in haploid form, for which a wide variety of molecular genetic tools are available, and that exhibits a simple, polarized secretory apparatus with a well-defined endoplasmic reticulum and Golgi that can serve as a model for understanding secretion. Got it? Now name a cell with all these attributes that contains at least a dozen distinct and morphologically well-defined intracellular organelles, including three distinct types of secretory vesicles and two endosymbiotic organelles. Not so sure anymore?

摘要

说出一种单细胞真核生物,它具有小基因组规模,易于以单倍体形式培养,有各种各样的分子遗传学工具可用,并且具有简单的、极化的分泌装置,其内质网和高尔基体定义明确,可作为理解分泌的模型。明白了吗?现在说出一个具有所有这些特征的细胞,它至少包含十二个不同的、形态上定义明确的细胞内细胞器,包括三种不同类型的分泌囊泡和两种内共生细胞器。不太确定了吧?

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5dc/2173860/cde005d4a150/0112144f1.jpg

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