Liang L, Korogi Y, Sugahara T, Ikushima I, Shigematsu Y, Okuda T, Takahashi M, Kochi M, Ushio Y
Department of Radiology, Kumamoto University School of Medicine, 1-1-1 Honjo, Japan.
Neuroradiology. 2002 May;44(5):382-8. doi: 10.1007/s00234-001-0752-0. Epub 2002 Jan 5.
Our aim was to review the MRI appearances of primary intracranial germ-cell tumours (GCT). We reviewed the MRI studies of 32 patients: 19 with germinomas, five with teratomas, one with an embryonal carcinoma, five with mixed and two with malignant nongerminomatous GCT. Eleven were in the pineal region, 12 suprasellar, five in the both sites, two in the basal ganglia and two in the corpus callosum. Contrast-enhanced images were available for 27 patients. The solid parts of GCT were nearly isointense with grey matter on both T1- and T2-weighted images. In seven patients with nongerminomatous GCT high-signal components were found on T1-weighted images, representing haemorrhage, high-protein fluid or fat. Cystic components were detected in 17 of 27 patients; eight germinomas and all nine nongerminomatous GCT had cysts. The solid components of germinomas enhanced homogeneously in eight cases and heterogeneously in 10, while all nongerminomatous GCT showed heterogeneous enhancement. MRI features tumours can facilitate correct diagnosis of GCT, including histological subtypes.
我们的目的是回顾原发性颅内生殖细胞肿瘤（GCT）的MRI表现。我们回顾了32例患者的MRI研究：19例为生殖细胞瘤，5例为畸胎瘤，1例为胚胎癌，5例为混合性，2例为恶性非生殖细胞性GCT。11例位于松果体区，12例位于鞍上，5例位于两个部位，2例位于基底节，2例位于胼胝体。27例患者有增强扫描图像。GCT的实性部分在T1加权和T2加权图像上与灰质几乎等信号。7例非生殖细胞性GCT患者在T1加权图像上发现高信号成分，代表出血、高蛋白液体或脂肪。27例患者中有17例检测到囊性成分；8例生殖细胞瘤和所有9例非生殖细胞性GCT都有囊肿。生殖细胞瘤的实性成分8例呈均匀强化，10例呈不均匀强化，而所有非生殖细胞性GCT均呈不均匀强化。MRI特征有助于GCT的正确诊断，包括组织学亚型。
