Kanra Güler, Kara Ates, Seçmeer Gülten, Ozen Hasan, Gürakan Figen, Akçören Zuhal, Atas Ahmet
Department of Paediatrics, Hacettepe University School of Medicine, Ankara, Turkey.
Eur J Pediatr. 2002 Apr;161(4):216-8. doi: 10.1007/s00431-001-0909-1.
Inflammatory bowel disease is becoming increasingly frequent in children of all ages. In addition to the usual gastrointestinal stigmata of weight loss, anaemia, and rectal bleeding, children may exhibit prominent extra-intestinal manifestations such as joint symptoms, skin signs and some other auto-immune manifestations. Here we present a 15-year-old girl with ulcerative colitis in whom pyoderma gangrenosum and acute sensorineural hearing loss developed.
Although pyoderma gangrenosum is well described with inflammatory bowel disease, sensorineural hearing loss a is very unusual finding, possibly of auto-immune aetiology. We recommend steroid or immunosuppressive therapy in such a patient.
炎症性肠病在各年龄段儿童中越来越常见。除了常见的胃肠道症状如体重减轻、贫血和直肠出血外，儿童还可能出现明显的肠外表现，如关节症状、皮肤体征和其他一些自身免疫表现。在此，我们报告一名15岁患有溃疡性结肠炎的女孩，她出现了坏疽性脓皮病和急性感音神经性听力损失。
虽然坏疽性脓皮病与炎症性肠病相关已有充分描述，但感音神经性听力损失是非常罕见的发现，可能由自身免疫病因引起。我们建议对此类患者采用类固醇或免疫抑制治疗。
