唐氏综合征婴儿的自身免疫性甲状腺炎

Autoimmune thyroiditis in infants with Down's syndrome.

作者信息

Shalitin Shlomit, Phillip Moshe

机构信息

Institute of Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Petah Tiqva.

出版信息

J Pediatr Endocrinol Metab. 2002 May;15(5):649-52. doi: 10.1515/jpem.2002.15.5.649.

DOI:10.1515/jpem.2002.15.5.649

PMID:12014525

Abstract

Children with Down's syndrome are at high risk of thyroid dysfunction, including autoimmune thyroiditis. We describe two infants with Down's syndrome in whom chronic autoimmune thyroiditis was diagnosed at ages 5 months and 8 months. We suggest that follow-up of thyroid function and thyroid autoantibodies should be started from infancy in Down's syndrome to prevent further deterioration of mental development and growth.

摘要

唐氏综合征患儿患甲状腺功能障碍的风险很高，包括自身免疫性甲状腺炎。我们描述了两名唐氏综合征婴儿，他们分别在5个月和8个月大时被诊断出患有慢性自身免疫性甲状腺炎。我们建议，对于唐氏综合征患儿，应从婴儿期开始对甲状腺功能和甲状腺自身抗体进行随访，以防止智力发育和生长进一步恶化。