Suppr超能文献

[原发性心肌病的多中心流行病学调查。基于380例病例]

[Multicenter epidemiological survey of primary myocardiopathies. Apropos of 380 cases].

作者信息

Leclercq J F, Samuel J L, Mérillon J P, Eschwege E, Bertrand M, Gourgon R, Grosgogeat Y, Bouvrain Y, Swynghedauw B

出版信息

Arch Mal Coeur Vaiss. 1979 Dec;72(12):1302-10.

PMID:120146
Abstract

A retrospective study of adult congestive cardiomyopathy was carried out; the admission criteria being heart failure with cardiomegaly after the exclusion of known causes of heart failure. Coronary artery disease was excluded by forming two sub groups, one with proven normal coronary arteries at angiography or autopsy and the other with only assumedly normal coronary arteries. The results concern the study of the incidence of this disease which has been regularly seen over the last 10 years in departments with a large number of referrals of cardiomyopathy. --Professional factors are analysed to see if there is a higher incidence amongst the working classes. --Other factors are analysed by comparison with three control groups: normal, coronary and valvular disease, and diabetes which may be a predisposing factor, but not the serum cholesterol which is decreased in these patients. There is a significant association with smoking and alcoholism and the main biological sign of the latter condition, macrocytosis. This is also found in both coronary sub groups. The isolation of this alcohol factor in the genesis of congestive cardiomyopathy implies the possibility of reversing or stabilising the myocardial damage after its withdrawal, so changing the severe diagnosis associated with this disease.

摘要

对成人充血性心肌病进行了一项回顾性研究;纳入标准为排除已知心力衰竭病因后出现心力衰竭伴心脏扩大。通过形成两个亚组排除冠状动脉疾病,一组在血管造影或尸检时证实冠状动脉正常,另一组仅假定冠状动脉正常。研究结果涉及该病发病率的研究,在过去10年中,在大量转诊心肌病患者的科室中经常见到这种疾病。——分析职业因素,以观察工人阶级中的发病率是否更高。——通过与三个对照组进行比较分析其他因素:正常组、冠状动脉疾病组、瓣膜疾病组以及可能是易感因素的糖尿病组,但不包括这些患者中降低的血清胆固醇。吸烟和酗酒以及后者的主要生物学体征巨细胞症与之有显著关联。在两个冠状动脉亚组中也发现了这一点。在充血性心肌病的发病机制中分离出这种酒精因素意味着在戒酒之后有可能逆转或稳定心肌损伤,从而改变与该病相关的严重诊断。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验