Valty J, Ruiz E, Guermonprez J L, Forman J, Dauptain J, Patron G, Métral S, Wagniart P, Bickert P, Guérinon J
Arch Mal Coeur Vaiss. 1978 Apr;71(4):437-46.
A prospective study into the aetiology of presumed primary non-obstructive cardiomyopathy was carried out in 57 patients who had no lesions of the trunk of the coronary artery; one case of haemochromatosis and one of amyloidosis were found. Excluding these two cases of cardiomyopathy which were in fact secondary, most of the others were associated with manifestations or with complications of myocardial diseases (two pulmonary emboli and one case of jaundice) or pathology associated with it. Investigation into possible infection, biochemical abnormalities and dietary indiscretion (alcohol, colza oil), were unfruitful. Electromyographic changes of the "myositic" type were very common. The bicycle ergometry test was often interrupted through fatiguing of the peripheral muscles. These findings suggest that the muscular abnormalities may not be limited to the heart. The cost of an enquiry of this type has been investigated.
对57例冠状动脉主干无病变的疑似原发性非梗阻性心肌病患者进行了病因学前瞻性研究;发现1例血色素沉着症和1例淀粉样变性。排除这2例实际上为继发性的心肌病病例后,其他大多数病例与心肌疾病的表现或并发症(2例肺栓塞和1例黄疸)或与之相关的病理学有关。对可能的感染、生化异常和饮食不当(酒精、菜籽油)的调查均无结果。“肌炎样”类型的肌电图改变非常常见。自行车测力计测试常因外周肌肉疲劳而中断。这些发现表明,肌肉异常可能不限于心脏。已对这类调查的成本进行了研究。