Wasserman G A, Haberman H F
Can Med Assoc J. 1975 Dec 13;113(11-12):1055-60.
Between January 1972 and December 1974, 250 patients were referred for investigation of possible photosensitivity to a university-associated clinical research unit for photobiology. In addition to an appropriate history and clinical examination, phototesting was carried out with a solar simulator, monochromatic light and fluorescent light directed to patch-tested areas of skin. Photosensitivity was not demonstrated in 110 patients (44%). Among the laboratory-confirmed photosensitivities, diagnoses included polymorphous light eruption (4.4%), erythropoietic protoporphyria (3.6%), porphyria cutanea tarda (2%), photoallergic contact dermatitis (5.6%), persistent light reaction (4%), systemic drug phototoxicity (1.2%), phototoxic contact dermatitis (2%), solar urticaria (0.8%) and photoaggravated dermatoses (7.6%). It is important to establish a precise etiologic diagnosis in patients with photosensitivity in order to treat the disorder specifically or effectively or both.
在1972年1月至1974年12月期间，250名患者因可能存在光敏感问题被转诊至一所大学附属的光生物学临床研究单位进行检查。除了进行适当的病史询问和临床检查外，还使用太阳模拟器、单色光和荧光对皮肤斑贴试验区域进行了光测试。110名患者（44%）未表现出光敏感。在实验室确诊的光敏感病例中，诊断包括多形性日光疹（4.4%）、红细胞生成性原卟啉症（3.6%）、迟发性皮肤卟啉症（2%）、光变应性接触性皮炎（5.6%）、持久性光反应（4%）、全身性药物光毒性（1.2%）、光毒性接触性皮炎（2%）、日光性荨麻疹（0.8%）和光加重性皮肤病（7.6%）。对光敏感患者进行精确的病因诊断很重要，以便针对性地治疗该疾病，或有效治疗，或两者兼顾。
