Guo Y, Lin L, Shen J
Hainan Medical College, Haikou 570102.
Yao Xue Xue Bao. 1998 May;33(5):350-4.
Tinospora hainanesis is a new species of Menispermaceae plant. It is used as folk remedy for joint pain and physical injury. Five compounds were isolated from the vine stalk of Tinospora hainanesis. By spectral analysis and chemical methods, the structures of the compounds were identified as makisterone A (I), 2,3-dimethoxy-9,10-dihydroxy-N-methyltetrahydroproto-berberine quaternary salt (II), palmatine (III), beta-amyrin (IV) and docosyl ferulate (V). II is a new quaternary alkaloid named as haitinosporine. I, IV and V were isolated for the first time from the plants of Tinospora genus.
海南青牛胆是防己科植物的一个新物种。它被用作治疗关节疼痛和身体损伤的民间药物。从海南青牛胆的藤茎中分离出了五种化合物。通过光谱分析和化学方法，确定这些化合物的结构分别为玛可甾酮A（I）、2,3-二甲氧基-9,10-二羟基-N-甲基四氢原小檗碱季铵盐（II）、巴马汀（III）、β-香树脂醇（IV）和二十二烷基阿魏酸酯（V）。II是一种新的季铵生物碱，命名为海南青牛胆碱。I、IV和V首次从青牛胆属植物中分离得到。
