Kong L Y, Min Z D
Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing.
Yao Xue Xue Bao. 1996;31(7):524-9.
Nine compounds were isolated from the roots of Euphorbia pekinensis Rupr., a traditional Chinese medicine. By combination of chemical methods and spectral analyses, the structures of the compounds were identified as lanosterol (I), octadecanyl-3-methoxy-4-hydroxybenzeneacrylate (II), beta-sitosterol (III), 7-hydroxycoumarin (IV), 2, 2'-dimethoxy-3, 3'-dihydroxy-5, 5'-oxygen-6, 6'-biphenylformic anhydride (V), d-pinoresinol (VI), quercetin (VII), 3, 4-dimethoxybenzoic acid (VIII) and 3, 4-dihydroxybenzoic acid (IX). II and V are new compounds which have not been reported in the literature. The other compounds were isolated for the first time from this plant. VI is a lignan which was first isolated from the plants of genus of Euphorbia.
从传统中药大戟的根中分离出了9种化合物。通过化学方法和光谱分析相结合,确定这些化合物的结构分别为羊毛甾醇(I)、十八烷基-3-甲氧基-4-羟基苯丙烯酸酯(II)、β-谷甾醇(III)、7-羟基香豆素(IV)、2,2'-二甲氧基-3,3'-二羟基-5,5'-氧-6,6'-联苯二甲酸酐(V)、d-松脂醇(VI)、槲皮素(VII)、3,4-二甲氧基苯甲酸(VIII)和3,4-二羟基苯甲酸(IX)。II和V是文献中尚未报道的新化合物。其他化合物首次从该植物中分离得到。VI是一种木脂素,首次从大戟属植物中分离得到。