Tsai Hsiu-Nan, Wu Wen-Jeng, Huang Shu-Pin, Su Chin-Ming, Chen Chung-Chin, Wang Chii-Jye, Chou Yii-Her, Huang Chun-Hsiung
Department of Urology, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Rd., Kaohsiung 807, Taiwan.
Kaohsiung J Med Sci. 2002 Jan;18(1):39-44.
Herpes zoster infection involving the sacral dermatomes has been associated with bladder dysfunction and, although rarely, with acute urinary retention. Less than 150 cases have been reported in the literature. After reviewing our institute's chart records covering a period of time dating from 1991 to 2001, we found that three of our patients had developed acute urinary retention following herpes zoster skin lesions of the S2-4 dermatomes. Herein we report our findings. These three patients had previously been found to have normal voiding status. However, at the time of complaint urodynamic studies revealed detrusor areflexia or detrusor hyporeflexia with decreased sensation of bladder filling. After micturation recovery, repeat urodynamic studies revealed detrusor pressure and bladder sensation recovery. After one to six weeks of treatment, all three patients could void spontaneously without catheterization. We found that, when treated with antiviral medication, supportive analgesics, and temporary urinary drainage, which included urethral catheterization and suprapubic cystostomy, acute urinary retention associated with herpes zoster has a generally favorable prognosis. In other words, we found that in spite of its rarity, herpes zoster induced neuropathic bladder dysfunction is reversible when treated appropriately.
累及骶部皮节的带状疱疹感染与膀胱功能障碍有关,虽较为罕见,但可导致急性尿潴留。文献报道的病例不足150例。回顾我院1991年至2001年期间的病历记录,我们发现有3例患者在S2 - 4皮节带状疱疹皮肤损害后出现急性尿潴留。在此我们报告我们的发现。这3例患者之前排尿状态正常。然而,在出现症状时,尿动力学研究显示逼尿肌无反射或逼尿肌反射减退,膀胱充盈感觉减退。排尿恢复后,重复尿动力学研究显示逼尿肌压力和膀胱感觉恢复。经过1至6周的治疗,所有3例患者均能自行排尿而无需导尿。我们发现,当采用抗病毒药物、支持性镇痛药物以及包括尿道插管和耻骨上膀胱造瘘术在内的临时尿液引流治疗时,与带状疱疹相关的急性尿潴留通常预后良好。换句话说,我们发现尽管带状疱疹诱发的神经源性膀胱功能障碍罕见,但经过适当治疗是可逆的。