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长期喂食乙醇后大鼠肠道中表面活性剂样颗粒的形成。

Formation of surfactant-like-particle in rat intestine following chronic ethanol feeding.

作者信息

Kumar S, Mahmood S, Nagpaul J P, Mahmood A

机构信息

Department of Biochemistry, Panjab University, Chandigarh, India.

出版信息

Indian J Exp Biol. 2001 Aug;39(8):767-71.

Abstract

Ethanol feeding to rats daily for 40 days induces the secretion of surfactant-like-particles in intestine. The isolated lipoprotein particles were enriched with alkaline phosphatase activity and had high phosphatidylcholine content. There was no difference in disaccharidases activities associated with the particles from control and ethanol fed rats. These results suggest that ethanol induced surfactant-like-particles in rat intestine.

摘要

每天给大鼠喂食乙醇持续40天会诱导肠道中分泌表面活性剂样颗粒。分离出的脂蛋白颗粒富含碱性磷酸酶活性且磷脂酰胆碱含量高。来自对照大鼠和喂食乙醇大鼠的颗粒所关联的双糖酶活性没有差异。这些结果表明乙醇可诱导大鼠肠道产生表面活性剂样颗粒。

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