Suppr超能文献

俄罗斯结核病治疗方案与短程化疗的成本效益分析:来自西伯利亚托木斯克的结果。

Cost-effectiveness analysis of the russian treatment scheme for tuberculosis versus short-course chemotherapy: results from Tomsk, Siberia.

作者信息

Jacobs B, Clowes C, Wares F, Polivakho V, Lyagoshina T, Peremitin G, Banatvala N

机构信息

Merlin (Medical Emergency Relief International), Borough, London, UK.

出版信息

Int J Tuberc Lung Dis. 2002 May;6(5):396-405.

Abstract

SETTING

Tomsk Oblast, Siberia.

OBJECTIVE

To assess the cost-effectiveness of individualised Russian treatment and short-course chemotherapy (SCC) regimens for new WHO Category I tuberculosis patients.

DESIGN

Analysis of costs incurred by the provider, the household and society as a whole for both treatment approaches, and a sensitivity analysis for SCC with hospitalisation for 2 weeks (patients theoretically at low risk of defaulting) and 2 months (patients theoretically at risk of defaulting). Outcomes were measured as cost per case cured and year of life saved, with cure rates based on a locally conducted trial.

RESULTS

The cost per cure using the individualised Russian treatment was US $2,295, vs. US $1,901 when using SCC. The costs per year of life saved were respectively US $123 and US $103. The cost per cure was US $1,457 for SCC with 2 months hospitalisation and US $556 for SCC with 2 weeks hospitalisation, with costs per year of life saved of US $79 and US $30, respectively.

CONCLUSION

Major financial savings for both the provider and the household, with cure rates similar to those obtained with the Russian treatment scheme, can be achieved in Tomsk when embarking on SCC with 2 weeks and 2 months hospitalisation.

摘要

背景

俄罗斯西伯利亚托木斯克州。

目的

评估针对世界卫生组织新分类的I类结核病患者采用个体化俄罗斯治疗方案和短程化疗(SCC)方案的成本效益。

设计

分析两种治疗方法中医疗机构、家庭及整个社会所产生的成本,并对SCC进行敏感性分析,分别假设住院2周(理论上患者违约风险较低)和2个月(理论上患者有违约风险)。结果以每治愈一例的成本和挽救的生命年数来衡量,治愈率基于当地开展的一项试验。

结果

采用个体化俄罗斯治疗方案每治愈一例的成本为2295美元,而采用SCC时为1901美元。每挽救一年生命的成本分别为123美元和103美元。对于住院2个月的SCC,每治愈一例的成本为1457美元,而住院2周的SCC为556美元,每挽救一年生命的成本分别为79美元和30美元。

结论

在托木斯克,对于住院2周和2个月的SCC方案,医疗机构和家庭均可大幅节省资金,且治愈率与俄罗斯治疗方案相近。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验