Suppr超能文献

通过有限元方法研究冠状动脉支架的力学行为。

Mechanical behavior of coronary stents investigated through the finite element method.

作者信息

Migliavacca Francesco, Petrini Lorenza, Colombo Maurizio, Auricchio Ferdinando, Pietrabissa Riccardo

机构信息

Laboratory of Biological Structure Mechanics, Dipartimento di Bioingegneria, Politecnico di Milano, Piazza Leonardo da Vinci, 32, Milano 20133, Italy.

出版信息

J Biomech. 2002 Jun;35(6):803-11. doi: 10.1016/s0021-9290(02)00033-7.

Abstract

Intravascular stents are small tube-like structures expanded into stenotic arteries to restore blood flow perfusion to the downstream tissues. The stent is mounted on a balloon catheter and delivered to the site of blockage. When the balloon is inflated, the stent expands and is pressed against the inner wall of the coronary artery. After the balloon is deflated and removed, the stent remains in place, keeping the artery open. Hence, the stent expansion defines the effectiveness of the surgical procedure: it depends on the stent geometry, it includes large displacements and deformations and material non-linearity. In this paper, the finite element method is applied (i) to understand the effects of different geometrical parameters (thickness, metal-to-artery surface ratio, longitudinal and radial cut lengths) of a typical diamond-shaped coronary stent on the device mechanical performance, (ii) to compare the response of different actual stent models when loaded by internal pressure and (iii) to collect suggestions for optimizing the device shape and performance. The stent expansion and partial recoil under balloon inflation and deflation were simulated. Results showed the influence of the geometry on the stent behavior: a stent with a low metal-to-artery surface ratio has a higher radial and longitudinal recoil, but a lower dogboning. The thickness influences the stent performance in terms of foreshortening, longitudinal recoil and dogboning. In conclusion, a finite element analysis similar to the one herewith proposed could help in designing new stents or analyzing actual stents to ensure ideal expansion and structural integrity, substituting in vitro experiments often difficult and unpractical.

摘要

血管内支架是一种小的管状结构,被扩张到狭窄的动脉中,以恢复下游组织的血流灌注。支架安装在球囊导管上,并被输送到堵塞部位。当球囊充气时,支架扩张并被压在冠状动脉的内壁上。球囊放气并移除后,支架仍留在原位,保持动脉畅通。因此,支架扩张决定了手术的效果:它取决于支架的几何形状,包括大位移、变形和材料非线性。本文应用有限元方法:(i)了解典型菱形冠状动脉支架的不同几何参数(厚度、金属与动脉表面比、纵向和径向切割长度)对器械力学性能的影响;(ii)比较不同实际支架模型在内压加载时的响应;(iii)收集优化器械形状和性能的建议。模拟了球囊充气和放气时支架的扩张和部分回弹。结果显示了几何形状对支架行为的影响:金属与动脉表面比低的支架具有较高的径向和纵向回弹,但“狗骨化”程度较低。厚度在缩短、纵向回弹和“狗骨化”方面影响支架性能。总之,类似于本文所提出的有限元分析有助于设计新支架或分析实际支架,以确保理想的扩张和结构完整性,替代通常困难且不实用的体外实验。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验