• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Perspective: lessons learned from molecular genetic studies of thyroid cancer--insights into pathogenesis and tumor-specific therapeutic targets.

作者信息

Fagin James A

机构信息

Division of Endocrinology and Metabolism, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267-0547, USA.

出版信息

Endocrinology. 2002 Jun;143(6):2025-8. doi: 10.1210/endo.143.6.8832.

DOI:10.1210/endo.143.6.8832
PMID:12021165
Abstract
摘要

相似文献

1
Perspective: lessons learned from molecular genetic studies of thyroid cancer--insights into pathogenesis and tumor-specific therapeutic targets.观点:甲状腺癌分子遗传学研究的经验教训——对发病机制和肿瘤特异性治疗靶点的深入见解
Endocrinology. 2002 Jun;143(6):2025-8. doi: 10.1210/endo.143.6.8832.
2
RET oncogene puzzle in Chernobyl thyroid tumours.
Lancet. 1996 Apr 27;347(9009):1176. doi: 10.1016/s0140-6736(96)90626-1.
3
Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children.儿童辐射诱导性和散发性甲状腺乳头状癌形态学变异中ret原癌基因重排的独特模式。
Cancer Res. 1997 May 1;57(9):1690-4.
4
Targeted expression of the ret/PTC1 oncogene induces papillary thyroid carcinomas.ret/PTC1癌基因的靶向表达可诱导甲状腺乳头状癌。
Endocrinology. 1996 Jan;137(1):375-8. doi: 10.1210/endo.137.1.8536638.
5
Prevalence, significance, and biological behavior of ret/PTC1 associated papillary thyroid carcinoma.
J Clin Endocrinol Metab. 1997 May;82(5):1650. doi: 10.1210/jcem.82.5.3981-3.
6
A ret transgenic mouse model of thyroid carcinogenesis.一种甲状腺癌发生的RET转基因小鼠模型。
Lab Anim Sci. 1998 Dec;48(6):580-3.
7
High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation.在接受过外照射的患者的甲状腺肿瘤中,激活型原癌基因ret重排的高发生率。
Oncogene. 1997 Sep;15(11):1263-73. doi: 10.1038/sj.onc.1200206.
8
The ret/PTC oncogene in papillary thyroid carcinoma.甲状腺乳头状癌中的ret/PTC癌基因。
J Lab Clin Med. 1994 Mar;123(3):331-7.
9
Association of RET codon 691 polymorphism in radiation-induced human thyroid tumours with C-cell hyperplasia in peritumoural tissue.辐射诱导的人类甲状腺肿瘤中RET密码子691多态性与瘤周组织中C细胞增生的关联。
Br J Cancer. 2002 Jun 17;86(12):1929-36. doi: 10.1038/sj.bjc.6600371.
10
Thyroid carcinoma: diagnostic and therapeutic approach; genetic background (review).甲状腺癌:诊断与治疗方法;遗传背景(综述)
Endocr Regul. 2000 Jun;34(2):99-113.

引用本文的文献

1
Long glucocorticoid-induced leucine zipper regulates human thyroid cancer cell proliferation.长糖皮质激素诱导亮氨酸拉链调节人甲状腺癌细胞增殖。
Cell Death Dis. 2018 Feb 21;9(3):305. doi: 10.1038/s41419-018-0346-y.
2
Effect of BMAP-28 on human thyroid cancer TT cells is mediated by inducing apoptosis.BMAP-28对人甲状腺癌TT细胞的作用是通过诱导凋亡来介导的。
Oncol Lett. 2015 Oct;10(4):2620-2626. doi: 10.3892/ol.2015.3612. Epub 2015 Aug 14.
3
In vitro and in vivo activity of cabozantinib (XL184), an inhibitor of RET, MET, and VEGFR2, in a model of medullary thyroid cancer.
卡博替尼(XL184)在甲状腺髓样癌模型中的体外和体内活性研究,卡博替尼是一种 RET、MET 和 VEGFR2 的抑制剂。
Thyroid. 2013 Dec;23(12):1569-77. doi: 10.1089/thy.2013.0137. Epub 2013 Sep 17.
4
IRF5 promotes the proliferation of human thyroid cancer cells.IRF5 促进人甲状腺癌细胞的增殖。
Mol Cancer. 2012 Apr 16;11:21. doi: 10.1186/1476-4598-11-21.
5
Cytogenomics of cancers: from chromosome to sequence.癌症的细胞基因组学:从染色体到序列。
Mol Oncol. 2010 Aug;4(4):309-22. doi: 10.1016/j.molonc.2010.06.003. Epub 2010 Jun 11.
6
Identification of differentially expressed genes in papillary thyroid cancers.甲状腺乳头状癌中差异表达基因的鉴定
Yonsei Med J. 2009 Feb 28;50(1):60-7. doi: 10.3349/ymj.2009.50.1.60. Epub 2009 Feb 24.
7
Distinguishing molecular markers in thyroid tumors: a tribute to Dr. Orlo Clark.甲状腺肿瘤中的分子标志物鉴别:向奥尔洛·克拉克博士致敬。
World J Surg. 2009 Mar;33(3):375-7. doi: 10.1007/s00268-008-9721-7.
8
A unique RET EXON 11 (G691S) polymorphism in an Indian patient with a collision tumor of the thyroid.印度一位甲状腺碰撞瘤患者中存在一种独特的 RET 外显子 11(G691S)多态性。
Diagn Pathol. 2007 Oct 16;2:39. doi: 10.1186/1746-1596-2-39.
9
The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells.RET/PTC-RAS-BRAF线性信号级联介导甲状腺癌细胞的运动性和促有丝分裂表型。
J Clin Invest. 2005 Apr;115(4):1068-81. doi: 10.1172/JCI22758. Epub 2005 Mar 10.
10
The oncogenic activity of RET point mutants for follicular thyroid cells may account for the occurrence of papillary thyroid carcinoma in patients affected by familial medullary thyroid carcinoma.RET 点突变对甲状腺滤泡细胞的致癌活性可能是家族性甲状腺髓样癌患者发生甲状腺乳头状癌的原因。
Am J Pathol. 2004 Aug;165(2):511-21. doi: 10.1016/S0002-9440(10)63316-0.