Battaglini Piero Paolo, Muzur Amir, Galletti Claudio, Skrap Miran, Brovelli Andrea, Fattori Patrizia
Center for Neuroscience, University of Trieste, Italy.
Exp Brain Res. 2002 Jun;144(3):419-22. doi: 10.1007/s00221-002-1099-4. Epub 2002 Apr 25.
In order to assess the role played by area V6A in visuomotor control, two adult green monkeys ( Cercopithecus aethiops) were subjected to small, bilateral lesions in the anterior bank of the parieto-occipital sulcus. Before and after the lesions, monkeys were tested for naturally designed reaching, grasping and picking-up pieces of food from various positions on a plate and from a differently oriented narrow slit. All movements were recorded with closed circuit TV and analysed offline on a single-photogram basis for defective reaching and wrist orientation. V6A lesions provoked parietal weakness, reluctance to move, and specific deficits in reaching, wrist orientation and grasping. Recovery from the observed deficits was rapid, even after a second, contralateral lesion was given, creating a bilateral lesion. Thus, together with previous anatomical and electrophysiological data, these results directly support the hypothesis that area V6A is part of the network involved in the control of reaching movements and wrist orientation.
为了评估V6A区在视觉运动控制中所起的作用，对两只成年绿猴（猕猴）的顶枕沟前缘进行了双侧小面积损伤。在损伤前后，测试猴子从盘子上不同位置以及从不同方向的狭窄缝隙中自然地伸手抓取和拿起食物的能力。所有动作都用闭路电视记录，并在离线状态下基于单帧照片分析其伸手动作和手腕方向的缺陷。V6A区损伤引发了顶叶功能减弱、运动迟缓，以及伸手、手腕方向和抓握方面的特定缺陷。即使在对侧进行第二次损伤造成双侧损伤后，观察到的缺陷恢复也很快。因此，结合先前的解剖学和电生理学数据，这些结果直接支持了以下假设：V6A区是参与控制伸手动作和手腕方向的神经网络的一部分。
