Stewart S M, McBride W H
Rheumatology. 1975;6:329-37.
The failure to isolate conventional mycoplasmas from 88 synovial membranes and 119 synovial fluids from patients with proven rheumatoid arthritis using a variety of culture media and techniques agrees with the results of recent workers and suggests that these organisms are unlikely to play a role in the aetiology of the disease. In contrast, 'diphtheroid' organisms were isolated from 27 to 30% of rheumatoid specimens, but not from cultures of non-rheumatoid material. A significantly higher incidence of raised agglutination titres to C. acnes and to a 'diptheroid' isolated from a patient with rheumatoid arthritis in sera from patients with rheumatoid arthritis supports the conclusion that these organisms are present in the joints in such patients, though their role in this disease has yet to be established.
采用多种培养基和技术，未能从88例经证实患有类风湿性关节炎患者的滑膜及119例滑膜液中分离出传统支原体，这与近期其他研究者的结果一致，提示这些微生物不太可能在该疾病的病因学中起作用。相比之下，从27%至30%的类风湿标本中分离出了“类白喉”微生物，但在非类风湿材料的培养物中未分离出。类风湿性关节炎患者血清中对痤疮丙酸杆菌及从一名类风湿性关节炎患者分离出的“类白喉”微生物的凝集滴度升高的发生率显著更高，这支持了这些微生物存在于此类患者关节中的结论，尽管它们在该疾病中的作用尚未确定。
