Synthetic route to the GE3 cyclodepsipeptide.
作者信息
Hale Karl J, Lazarides Linos
机构信息
The Christopher Ingold Laboratories, Department of Chemistry, University College London, 20 Gordon Street, London WC1H 0AJ, United Kingdom.
出版信息
Org Lett. 2002 May 30;4(11):1903-6. doi: 10.1021/ol025895u.
PMID:12027643
Abstract
[reaction: see text] A reasonably efficient [2 + 2 + 2] fragment condensation strategy has been developed for assembling the cyclodepsipeptide sector of GE3 that involves 5-7. A Carpino HATU-mediated macrolactamization was used to close the 19-membered cyclodepsipeptide ring.
摘要
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