λ噬菌体N蛋白在体内进行转录抗终止作用对NusG的需求。
Requirement for NusG for transcription antitermination in vivo by the lambda N protein.
作者信息
Zhou Ying, Filter Joshua J, Court Donald L, Gottesman Max E, Friedman David I
机构信息
Department of Microbiology and Immunology, The University of Michigan, Medical School, Ann Arbor, Michigan 48109-0620, USA.
出版信息
J Bacteriol. 2002 Jun;184(12):3416-8. doi: 10.1128/JB.184.12.3416-3418.2002.
Abstract
Transcription antitermination by the bacteriophage lambda N protein is stimulated in vitro by the Escherichia coli NusG protein. Earlier work suggested that NusG was not required for N activity in vivo. Here we present evidence that NusG also stimulates N-mediated transcription antitermination in intact cells.
摘要
噬菌体λ N 蛋白的转录抗终止作用在体外受到大肠杆菌 NusG 蛋白的刺激。早期研究表明，NusG 在体内对于 N 的活性并非必需。在此我们提供证据表明，NusG 在完整细胞中也能刺激 N 介导的转录抗终止作用。
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