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对生活在日本、夏威夷和加利福尼亚的日本男性冠心病和中风的流行病学研究:血压分布情况

Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: blood pressure distributions.

作者信息

Winkelstein W, Kagan A, Kato H, Sacks S T

出版信息

Am J Epidemiol. 1975 Dec;102(6):502-13. doi: 10.1093/oxfordjournals.aje.a112188.

Abstract

Blood pressure measurements were made on three Japanese populations residing in Japan, Honolulu, and Northern California. A common protocol was utilized in an effort to standardize inter-observer variability. Zero terminal digit preference varied among the three areas and there was differential clustering of diastolic values at 80 mm Hg and 90 mm Hg in Hawaii and California, respectively. Diastolic blood pressure did not rise with age in any of the three populations while systolic blood pressure rose in each. Blood pressure levels in Japanese in Japan were intermediate to those in Hawaiian and Northern California Japanese, California having the higher blood pressure levels. Since the relative weights of the Japanese migrants to Hawaii and California were substantially higher than the relative weights of the non-migrant populations in Japan, the blood pressures were adjusted for these differences. When this was done, most of the differences among the various study subgroups were explained. The findings indicate that the blood pressure distributions of the Japanese populations residing in Japan, Hawaii, and Northern California cannot of themselves account for the observed differences in coronary heart disease and stroke occurrence among these populations in which there is a gradient from high stroke rates in Japan to low rates in California and a reverse trend for coronary heart disease.

摘要

对居住在日本、檀香山和北加利福尼亚的三个日本人群进行了血压测量。采用了通用方案以努力使观察者间的变异性标准化。三个地区的零末位数字偏好各不相同,在夏威夷和加利福尼亚,舒张压值分别在80毫米汞柱和90毫米汞柱处存在差异聚类。在这三个人群中,没有一个人群的舒张压随年龄增长而升高,而收缩压在每个人群中都升高。日本本土日本人的血压水平介于夏威夷和北加利福尼亚日本人之间,加利福尼亚的血压水平更高。由于移民到夏威夷和加利福尼亚的日本人的相对权重显著高于日本本土非移民人群的相对权重,因此对这些差异进行了血压调整。这样做之后,各个研究亚组之间的大多数差异都得到了解释。研究结果表明,居住在日本、夏威夷和北加利福尼亚的日本人群的血压分布本身并不能解释这些人群中观察到的冠心病和中风发生率的差异,其中存在从日本的高中风率到加利福尼亚的低中风率的梯度,而冠心病则呈相反趋势。

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