Gennari S M, Yai L E O, D'Auria S N R, Cardoso S M S, Kwok O C H, Jenkins M C, Dubey J P
Faculdade de Medicina Veterinária e Zootecnia, Departamento de Medicina Veterinária Preventiva e Saúde Animal, Universidade de São Paulo, Av. Prof. Dr. Orlando Marques de Paiva, 87, Cidade Universitária, SP 05508-000, São Paulo, Brazil.
Vet Parasitol. 2002 Jun 3;106(2):177-9. doi: 10.1016/s0304-4017(02)00052-3.
Neospora caninum is an important cause of abortion in dairy cattle worldwide. Dogs are important in the epidemiology of this parasite because they are the only hosts known to excrete N. caninum oocysts. In order to understand the prevalence of N. caninum in dogs, sera from 500 owned dogs and from over 600 feral street dogs from the city of São Paulo, Brazil were assayed for antibodies to N. caninum. Sera were examined by the Neospora agglutination test (NAT) using mouse-derived tachyzoites. Antibodies (> or =1:25) to N. caninum were found in nearly 10% (49/500) of owned dogs and in 25% (151/611) of stray dogs. NAT titers for owned dogs were 1:25 in 28 (5.6%) dogs, 1:50 in 20 (4%) dogs, and > or =1:500 in 1 (0.2%) dog. NAT titers for stray dogs were 1:25 in 79 (12.9%) dogs, 1:50 in 68 (11.1%) dogs, and > or =1:500 in 4 (0.6%) dogs. These data indicate that feral dogs may be important in the epidemiology of N. caninum infection.
犬新孢子虫是全球奶牛流产的一个重要病因。犬在这种寄生虫的流行病学中很重要，因为它们是已知唯一能排出犬新孢子虫卵囊的宿主。为了解犬新孢子虫在犬中的流行情况，对来自巴西圣保罗市500只家养犬和600多只流浪犬的血清进行了犬新孢子虫抗体检测。血清通过使用小鼠来源速殖子的新孢子虫凝集试验（NAT）进行检测。在家养犬中，近10%（49/500）检测到犬新孢子虫抗体（≥1:25），流浪犬中这一比例为25%（151/611）。家养犬的NAT滴度为1:25的有28只（5.6%），1:50的有20只（4%），≥1:500的有1只（0.2%）。流浪犬的NAT滴度为1:25的有79只（12.9%），1:50的有68只（11.1%），≥1:500的有4只（0.6%）。这些数据表明，流浪犬在犬新孢子虫感染的流行病学中可能很重要。
