一种用于评估青光眼性损害的新型视盘分级量表的有效性：与视野损害的相关性

Validity of a new disk grading scale for estimating glaucomatous damage: correlation with visual field damage.

作者信息

Bayer Atilla, Harasymowycz Paul, Henderer Jeffrey D, Steinmann William G, Spaeth George L

机构信息

The William Anna Goldberg Glaucoma Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107-5598, USA.

出版信息

Am J Ophthalmol. 2002 Jun;133(6):758-63. doi: 10.1016/s0002-9394(02)01422-8.

DOI:10.1016/s0002-9394(02)01422-8

PMID:12036666

Abstract

PURPOSE

To determine the correlation of a new disk grading system, the disk damage likelihood scale (DDLS), with the visual field damage in patients with glaucoma.

DESIGN

Observational case series.

METHODS

Charts of 75 patients (150 eyes) with primary open-angle glaucoma (POAG), 41 patients (82 eyes) with low-tension glaucoma (LTG), and 25 patients (50 eyes) with pseudoexfoliative glaucoma (PXFG) were reviewed retrospectively. DDLS stages and vertical disk sizes were recorded. A masked observer staged the Humphrey field analyzer (program 24-2) visual fields using the Hodapp-Parrish-Anderson (HPA) visual field staging system. Mean deviation (MD) and pattern standard deviation (PSD) values were obtained. The correlation of DDLS with the visual field parameters and HPA staging system were evaluated. Findings were assessed by the Pearson and Spearman correlation coefficients.

RESULTS

In the 282 eyes studied, the DDLS was strongly correlated with both MD (Pearson r = - 0.695, P <.001) and PSD (Pearson r =.703, P <.001). The HPA visual field staging system was also strongly correlated with the DDLS (Spearman r =.711, P <.001). These relationships continued to be significant when the three diagnostic groups (POAG, LTG, PXFG) were evaluated separately (P <.001) and also for small (< 1.5 mm) and average size (1.5-2.0 mm) disks. Large disks (> 2.0 mm) were not evaluated, because there was an insufficient number of cases.

CONCLUSION

DDLS, a new system for estimating glaucomatous disk damage, strongly correlates with the degree of glaucomatous visual field damage.

摘要

目的

确定一种新的视盘分级系统——视盘损伤可能性量表（DDLS）与青光眼患者视野损伤之间的相关性。

设计

观察性病例系列。

方法

回顾性分析75例原发性开角型青光眼（POAG）患者（150只眼）、41例低眼压性青光眼（LTG）患者（82只眼）和25例剥脱性青光眼（PXFG）患者（50只眼）的病历。记录DDLS分期和视盘垂直径大小。一位盲态观察者使用Hodapp-Parrish-Anderson（HPA）视野分级系统对Humphrey视野分析仪（程序24-2）的视野进行分级。获取平均偏差（MD）和模式标准偏差（PSD）值。评估DDLS与视野参数及HPA分级系统的相关性。通过Pearson和Spearman相关系数评估结果。

结果

在研究的282只眼中，DDLS与MD（Pearson r = -0.695，P <.001）和PSD（Pearson r =.703，P <.001）均密切相关。HPA视野分级系统也与DDLS密切相关（Spearman r =.711，P <.001）。当分别评估三个诊断组（POAG、LTG、PXFG）时，这些关系仍然显著（P <.001），对于小视盘（<1.5 mm）和中等大小视盘（1.5 - 2.0 mm）也是如此。未对大视盘（>2.0 mm）进行评估，因为病例数量不足。