Cheng Kelvin K W, Tatham Andrew J
Princess Alexandra Eye Pavilion, Edinburgh, UK.
Clin Ophthalmol. 2021 Oct 7;15:4059-4071. doi: 10.2147/OPTH.S284618. eCollection 2021.
The disc damage likelihood scale (DDLS) is a tool for classifying glaucomatous structural changes to the optic disc based on the radial width of the neuroretinal rim at its thinnest location, or if no rim is present, the extent of absence of the rim. Unlike cup disc ratio (CDR), the DDLS also considers disc size. Twenty years after its first description, the aim of this review was to critically appraise evidence for the DDLS and evaluate its role in current practice. A literature search by two independent authors identified 33 relevant articles for inclusion. Five studies evaluated reproducibility, 5 diagnostic performance, and 2 studies examined ability to detect progression. Eleven studies evaluated correlation between DDLS and other markers of glaucoma. Despite the widespread availability of imaging devices such as optical coherence tomography (OCT), clinical examination of the optic disc remains an essential component of glaucoma diagnosis and monitoring. The DDLS provides a reliable method for semi-quantitative clinical grading of the optic disc in glaucoma, with higher reproducibility than methods such as CDR.
视盘损伤可能性量表（DDLS）是一种根据神经视网膜边缘最薄处的径向宽度，或在不存在边缘的情况下，边缘缺失的程度，对视盘的青光眼性结构变化进行分类的工具。与杯盘比（CDR）不同，DDLS还考虑了视盘大小。在其首次描述二十年后，本综述的目的是批判性地评估DDLS的证据，并评估其在当前实践中的作用。两位独立作者进行的文献检索确定了33篇相关文章以供纳入。五项研究评估了可重复性，五项评估了诊断性能，两项研究考察了检测进展的能力。十一项研究评估了DDLS与青光眼其他标志物之间的相关性。尽管光学相干断层扫描（OCT）等成像设备已广泛应用，但对视盘的临床检查仍然是青光眼诊断和监测的重要组成部分。DDLS为青光眼视盘的半定量临床分级提供了一种可靠的方法，其可重复性高于CDR等方法。
