Bornfeld N, Talies S, Anastassiou G, Schilling H, Schüler A, Horstmann G A
Universitätsklinikum Essen, Zentrum für Augenheilkunde, Abteilung für Erkrankungen des hinteren Augenabschnitts, Hufelandstrasse 55, 45122 Essen.
Ophthalmologe. 2002 May;99(5):338-44. doi: 10.1007/s00347-002-0647-4.
In cases of large volume and highly prominent melanomas of the uvea, it is rare for conventional methods of radiation therapy to enable salvage of the globe or even residual functionality of the affected eye. Complications due to the massive amount of accumulated necrotic tissue often necessitate subsequent enucleation of the blinded eye. Tumor-destroying, single-dose convergence irradiation (radiosurgery) of such tumors applied shortly before endoresection can represent a possible therapeutic alternative in these types of cases.
对于葡萄膜黑色素瘤体积大且极为突出的病例，传统放射治疗方法很少能挽救眼球，甚至难以保留患眼的残余功能。大量累积的坏死组织所引发的并发症常常使得后续不得不摘除失明的眼睛。在肿瘤切除术前不久对这类肿瘤进行肿瘤毁损性单剂量聚焦照射（放射外科手术）可能是这类病例的一种治疗选择。
