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聚合酶链反应检测眼眶结核病例中的结核分枝杆菌

Detection of Mycobacterium tuberculosis by polymerase chain reaction in a case of orbital tuberculosis.

作者信息

Biswas Jyotirmay, Roy Chowdhury Bani, Krishna Kumar S, Lily Therese K, Madhavan H N.

机构信息

Medical and Vision Research Foundation, Chennai, India

出版信息

Orbit. 2001 Mar;20(1):69-74. doi: 10.1076/orbi.20.1.69.2643.

DOI:10.1076/orbi.20.1.69.2643
PMID:12045936
Abstract

Orbital tuberculosis is quite uncommon. We report a case of orbital tuberculosis in a 3-year-old child from Bangladesh who presented with swelling and discharging sinus in the lower part of the orbit. Histopathology revealed a granulomatous inflammation with caseation necrosis. Polymerase chain reaction (PCR) showed amplification of the Mycobacterium tuberculosis genome. The patient responded to a course of antituberculous treatment. Mycobacterium tuberculosis should be considered in the differential diagnosis of inflammatory orbital disease in the Indian subcontinent where tuberculosis is prevalent.

摘要

眼眶结核相当罕见。我们报告一例来自孟加拉国的3岁儿童眼眶结核病例,该患儿表现为眼眶下部肿胀及有排脓窦道。组织病理学显示为伴有干酪样坏死的肉芽肿性炎症。聚合酶链反应(PCR)显示结核分枝杆菌基因组扩增。该患者对抗结核治疗疗程有反应。在结核病流行的印度次大陆,炎症性眼眶疾病的鉴别诊断中应考虑结核分枝杆菌。

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