一名11岁女孩急性过量服用喹硫平。

Acute quetiapine overdose in an eleven-year-old girl.

作者信息

Juhl Gregory A, Benitez John G, McFarland Susan

机构信息

Department of Emergency Medicine, University of Rochester Medical Center, NY 14642, USA.

出版信息

Vet Hum Toxicol. 2002 Jun;44(3):163-4.

PMID:12046970

Abstract

We present a case of acute Quetiapine (SeroQuel) overdose in an 11-y-old girl who ingested 1,300 mg (22.2 mg/kg bw). Initial lethargy developed within I h followed by an episode of agitation and combativeness 3 h after ingestion. After treatment with lorazepam the patient experienced extended somnolence followed by return to normal mental status 16 h after ingestion. No cardiotoxic or laboratory abnormalities were found. This is the first report of acute Quetiapine overdose in an adolescent and suggests a relatively benign clinical course.

摘要

我们报告一例11岁女孩急性过量服用喹硫平（思瑞康）的病例，她摄入了1300毫克（22.2毫克/千克体重）。服药后1小时内出现初始嗜睡，随后在服药3小时后出现一阵激动和攻击性。用劳拉西泮治疗后，患者经历了长时间的嗜睡，服药16小时后精神状态恢复正常。未发现心脏毒性或实验室异常。这是青少年急性喹硫平过量的首例报告，提示临床过程相对良性。