Pfleger S, Staedt U, Süselbeck T, Borggrefe M, Haase K K
I. Medizinische Klinik, Universitätsklinikum Mannheim.
MMW Fortschr Med. 2002 Apr 25;144(17):27-30.
The high mortality rate of acute myocardial infarction underline the importance of this entity in the differential diagnosis of acute chest pain. Medical history, clinical presentation, ECG, biochemical markers of myocardial injury and imaging techniques are used to establish a correct diagnosis. Myocardial infarction can be divided into ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction. In the case of ST-segment elevation myocardial infarction thrombolytic therapy or percutaneous transluminal coronary angioplasty should be instituted as soon as possible. In patients without persistent ST-segment elevation biochemical markers of myocardial damage, especially troponin T and troponin I, are of major importance for risk stratification. Patients with elevated troponin levels should be treated with GPIIb/IIIa antagonists and early intervention.
急性心肌梗死的高死亡率凸显了该疾病在急性胸痛鉴别诊断中的重要性。病史、临床表现、心电图、心肌损伤的生化标志物及影像学技术用于做出正确诊断。心肌梗死可分为ST段抬高型心肌梗死和非ST段抬高型心肌梗死。对于ST段抬高型心肌梗死,应尽快实施溶栓治疗或经皮冠状动脉腔内血管成形术。对于无持续性ST段抬高的患者,心肌损伤的生化标志物,尤其是肌钙蛋白T和肌钙蛋白I,对危险分层至关重要。肌钙蛋白水平升高的患者应接受糖蛋白IIb/IIIa拮抗剂治疗及早期干预。