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溃疡性结肠炎和克罗恩病中的肌肉细胞电解质

Muscle cell electrolytes in ulcerative colitis and Crohn's disease.

作者信息

Valentin N, Neilsen O V, Olesen K H

出版信息

Digestion. 1975;13(5):284-90. doi: 10.1159/000197720.

DOI:10.1159/000197720
PMID:1205015
Abstract

The intracellular electrolyte concentrations in skeletal muscle from 15 patients with ulcerative colitis or Crohn's disease were examined. In patients with diarrhea not receiving potassium, muscle cell potassium and magnesium were low and sodium insignificantly elevated. By contrast, largely normal muscle cell electrolyte concentrations were found in patients receiving potassium or having a normal intestinal function. Supported by the existence of normal muscle cell electrolytes in a control group of patients receiving prednisone for extraintestinal diseases it was stated that glucocorticoid treatment does not affect the muscle cell electrolytes unless such treatment is effective in controlling the intestinal function. Potassium - and possibly magnesium - supplementations are recommended in cases with diarrhea.

摘要

对15例溃疡性结肠炎或克罗恩病患者的骨骼肌细胞内电解质浓度进行了检测。在未补钾的腹泻患者中,肌肉细胞内钾和镁含量降低,钠含量轻度升高。相比之下,补钾或肠道功能正常的患者肌肉细胞电解质浓度基本正常。在一组因肠外疾病接受泼尼松治疗的对照患者中,其肌肉细胞电解质正常,这表明糖皮质激素治疗除非能有效控制肠道功能,否则不会影响肌肉细胞电解质。腹泻患者建议补钾,可能还需补镁。

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Muscle cell electrolytes in ulcerative colitis and Crohn's disease.溃疡性结肠炎和克罗恩病中的肌肉细胞电解质
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