Haglund U, Hultén L
Acta Chir Scand. 1976;142(2):160-4.
The protein content in serum and peritoneal fluid has been determined and analysed electrophoretically in patients with Crohn's disease and ulcerative colitis and the data obtained compared with previously published data on serum and ascites content in liver cirrhosis, heart failure and intestinal tuberculosis. Ascites fluid in liver cirrhosis and heart failure, representing a true transudate, had a comparatively low protein content while the ascites fluid in inflammatory bowel diseases including Crohn's disease had high protein content. There was no difference in ascites protein content or ascites/serum protein ratio between patients with Crohn's disease and patients with ulcerative colitis. An exudative nature of both these inflammatory bowel conditions appears to be the main cause to the peritoneal fluid often observed at laparotomy. It cannot be excluded, however, that a lymphatic stasis, which is thought to be involved in Crohn's disease, might at least partly contribute to the development when larger quantities of ascitic fluid are at hand in this disease.
对克罗恩病和溃疡性结肠炎患者的血清和腹腔积液中的蛋白质含量进行了测定，并通过电泳分析，将所得数据与先前发表的关于肝硬化、心力衰竭和肠结核患者血清和腹水含量的数据进行了比较。肝硬化和心力衰竭患者的腹水呈真性漏出液，蛋白质含量相对较低，而包括克罗恩病在内的炎症性肠病患者的腹水蛋白质含量较高。克罗恩病患者和溃疡性结肠炎患者的腹水蛋白质含量或腹水/血清蛋白比值没有差异。这两种炎症性肠病的渗出性质似乎是剖腹手术时经常观察到腹腔积液的主要原因。然而，不能排除在克罗恩病中被认为与之相关的淋巴淤滞，在该疾病出现大量腹水时，可能至少部分促成了腹水的形成。
