Grassi T, Lavezzaro G, Bevilacqua R
G Ital Cardiol. 1975;5(5):724-36.
The relationship between heart dynamic and the carotid pulse has been studied by using the second derivative as a function of the time of the carotid pulse. This method permits a detailed analysis of the systolic phase of the carotid pulse: in protosystole a positive wave preceeds a negative wave and in telesystole a negative wave preceeds a positive wave. The morphology of the acceleration carotid pulse (CDA Carotidogramma Di Accelerazione), represented by a series of formulas which relate between themselves the protosystolic and the telesystolic waves, is a characteristic as well as statistically significant in each class of the cardiovascular disease in which we examined aortic insufficiency and stenosis, mitral insufficiency and stenosis, aortic angiosclerosis and hypokinetic myocardiopathy. We propose the use of the CDA for a precise analysis of the process of contraction and relaxation of the left ventricle. Since the acceleration with which a phenomenon evolves is the expression of the strength that has generated it, the CDA is particularly effective for the study myocardial dynamic.
通过将二阶导数作为颈动脉搏动时间的函数，研究了心脏动力学与颈动脉搏动之间的关系。该方法能够对颈动脉搏动的收缩期进行详细分析：在收缩前期，一个正向波先于一个负向波出现；在舒张后期，一个负向波先于一个正向波出现。加速颈动脉搏动（CDA，即Carotidogramma Di Accelerazione）的形态由一系列将收缩前期波和舒张后期波相互关联的公式表示，在我们所研究的每一类心血管疾病中，包括主动脉瓣关闭不全和狭窄、二尖瓣关闭不全和狭窄、主动脉血管硬化和心肌运动减退，它都是一种具有特征性且在统计学上有显著意义的表现。我们建议使用CDA来精确分析左心室的收缩和舒张过程。由于一种现象演变的加速度是产生该现象的力量的体现，所以CDA对于研究心肌动力学特别有效。
