Gemelli A, Camerucci S, Di Benedetto P, Cardi L
Minerva Med. 1981 Oct 13;72(39):2611-6.
75 patients suffering from aortic valvulopathy without signs of left ventricular insufficiency have been examined. Left ventricular function is studied by determining systolic times with polygraphic examination (Q-S2, LVET and PEP). The ECG findings were assessed with a myocardial hypertrophy criterion based on a point-score system. Finally, the time of total carotidogram ascent, the 1/2 T and the distance between Q wave and acme of the systolic murmur (Q-acme) were measured. It is concluded that: 1) The most meaningful increases in LVET are associated with the most evident shortenings in PEP only in the phase of the disease in which left ventricular hypertrophy is at its height. 2) The delay in systolic wave ascent should be considered indicative of the functional haemodynamic importance of aortic stenosis, whereas the earliness or otherwise of systolic murmur acme is an expression of the anatomic extent of the stenosis in question.
对75例无左心室功能不全体征的主动脉瓣病变患者进行了检查。通过多导仪检查测定收缩期时间（Q-S2、左心室射血时间[LVET]和射血前期[PEP]）来研究左心室功能。根据基于评分系统的心肌肥厚标准评估心电图结果。最后，测量颈总动脉造影上升总时间、1/2 T以及Q波与收缩期杂音顶点之间的距离（Q-顶点）。得出以下结论：1）仅在左心室肥厚达到高峰的疾病阶段，LVET最显著的增加与PEP最明显的缩短相关。2）收缩波上升延迟应被视为主动脉瓣狭窄功能性血流动力学重要性的指标，而收缩期杂音顶点的提前或其他情况则是所讨论狭窄解剖范围的一种表现。
