Zák J
Gerontologická klinika 1. LF UK a VFN, Praha.
Cas Lek Cesk. 2002 Apr 12;141(7):203-6.
Prevention of fractures brings about the effort to eliminate their potential causes. Osteoporosis syndrome belongs to the most frequent causes of the bone fractures. The use of densitometric methods may bring an overestimation of the bone quantity. Because of the independent contribution to mechanical resistance, the bone quality needs to be also evaluated. Qualitative changes of the bone can occur at the level of the bone as an organ, or at levels of its components--cortex, spongiosis and bone matrix. Bone quality is influenced mainly genetically; however, it can deteriorate also with age or in some diseases. Measurement of the bone quality is not yet practically accessible. Some ultrasonographic methods have a character of qualitative assessment. Osteoporosis can worsen the bone quality at different levels.
预防骨折需要努力消除其潜在原因。骨质疏松综合征是导致骨折最常见的原因之一。骨密度测量方法可能会高估骨量。由于骨质量对机械阻力有独立贡献，因此也需要对其进行评估。骨的质量变化可发生在作为一个器官的骨水平，或其组成部分——皮质骨、松质骨和骨基质的水平。骨质量主要受遗传影响；然而，它也会随着年龄增长或在某些疾病中恶化。目前骨质量的测量在实际应用中还无法实现。一些超声检查方法具有定性评估的特点。骨质疏松可在不同水平上使骨质量恶化。
