Hempenstall Kathleen, Rice Andrew S C
Department of Anaesthetics, The Hillingdon Hospital, Uxbridge, Middlesex, UK.
Curr Opin Investig Drugs. 2002 Mar;3(3):441-8.
Neuropathic pain results from damage to the nervous system due to many diverse processes. It causes persistent, distressing pain that is reputedly unresponsive to conventional analgesics. Treatment is best managed in a multi-therapy pain clinic setting and pharmacotherapy is one facet of this treatment. There is no single effective drug treatment and patients have been empirically treated with antidepressants and antiepileptics in the past. This review focuses on evidence from randomized controlled trials to assess the efficacy of the currently available drug treatments.
神经性疼痛是由多种不同过程导致的神经系统损伤引起的。它会引发持续且令人痛苦的疼痛，据说对传统镇痛药无反应。在多疗法疼痛诊所环境中进行治疗效果最佳，药物治疗是这种治疗的一个方面。没有单一有效的药物治疗方法，过去患者一直凭经验用抗抑郁药和抗癫痫药进行治疗。本综述聚焦于随机对照试验的证据，以评估当前可用药物治疗的疗效。
