低强度脉冲超声对生物可吸收自增强聚L-丙交酯螺钉的影响。

The effects of low-intensity pulsed ultrasound on bioabsorbable self-reinforced poly L-lactide screws.

作者信息

Handolin Lauri, Pohjonen Timo, Partio Esa K, Arnala Ilkka, Törmälä Pertti, Rokkanen Pentti

机构信息

Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Finland.

出版信息

Biomaterials. 2002 Jul;23(13):2733-6. doi: 10.1016/s0142-9612(02)00006-6.

DOI:10.1016/s0142-9612(02)00006-6

PMID:12059023

Abstract

The effects of low-intensity pulsed ultrasound on the mechanical and molecular properties of self-reinforced poly L-lactide (SR-PLLA) screws were studied in vitro. SR-PLLA screws of 4.5 mm diameter were exposed on low-intensity ultrasound for 1, 3. 6, 9, and 12 weeks. After exposure, the bending strength, shear strength, and molecular weight were investigated. There were no differences in the investigated properties between the ultrasound exposure and control groups. We found no evidence that low-intensity ultrasound has any effect on the mechanical or molecular properties of SR-PLLA screws in vitro. The present results suggest that biodegradable SR-PLLA fixation devices are compatible with low-intensity ultrasound in vitro.

摘要

体外研究了低强度脉冲超声对自增强聚L-丙交酯（SR-PLLA）螺钉力学和分子性能的影响。将直径4.5 mm的SR-PLLA螺钉暴露于低强度超声下1、3、6、9和12周。暴露后，研究其弯曲强度、剪切强度和分子量。超声暴露组和对照组在研究性能方面没有差异。我们没有发现证据表明低强度超声在体外对SR-PLLA螺钉的力学或分子性能有任何影响。目前的结果表明，可生物降解的SR-PLLA固定装置在体外与低强度超声兼容。