Khan N A, Donhuijsen K
HNO. 1975 Jul;23(7):210-2.
To summarise our morphological findings of this study the following conclusions are drawn: In bone grafts growth of vital cells originating from the Haversian canals is clearly demonstrated. The growth of connective tissue in the Haversian system is understandable on general principles of pathology. The morphology of the change of osteocytes from fibrocytes through osteoblasts is photographically clearly shown and is in keeping with the findings of Steinbach and of Kerr and Smyth. New bone formation was detected at earliest nine months after implantation. Our investigations do not confirm whether this new bone formation occurs persistently in all cases or to what extent the original homograft material, preserves in cialit solution, takes part in this process. A similar mechanism of tissue regrowth should be accepted in homograft cartilage. We have studied two cases, one after 6 months and the other after 5 years following implant. The three fascial grafts examined compare with earlier publications, with oedema, slight inflammation and little shrinkage occurring. The suitability for grafting of homograft incus, cartilage and fascia we believe to have been demonstrated.
为总结本研究的形态学发现,得出以下结论:在骨移植中,清楚地证明了源自哈弗斯管的活细胞的生长。哈弗斯系统中结缔组织的生长基于病理学的一般原理是可以理解的。从纤维细胞通过成骨细胞转变的骨细胞形态在照片上清晰显示,并且与斯坦巴赫以及克尔和史密斯的研究结果一致。最早在植入后九个月检测到新骨形成。我们的研究未证实这种新骨形成是否在所有情况下持续发生,或者保存在cialit溶液中的原始同种异体移植材料在多大程度上参与了这一过程。同种异体移植软骨中应接受类似的组织再生机制。我们研究了两个病例,一个在植入后6个月,另一个在植入后5年。检查的三块筋膜移植物与早期出版物相比,出现了水肿、轻微炎症和少量收缩。我们认为同种异体砧骨、软骨和筋膜的移植适用性已得到证明。