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J Clin Pathol. 1975 Dec;28(12):1000-2. doi: 10.1136/jcp.28.12.1000.
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CHEMICAL COMPOSITION OF CELL-WALL PREPARATIONS FROM STRAINS OF VARIOUS FORM-GENERA OF AEROBIC ACTINOMYCETES.需氧放线菌不同形态属菌株细胞壁制剂的化学成分
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2
PRECIPITIN (F.L.H.) TEST IN FARMER'S LUNG.农民肺中的沉淀素（F.L.H.）试验
Thorax. 1965 Jan;20(1):21-35. doi: 10.1136/thx.20.1.21.
3
FARMER'S LUNG. THERMOPHILIC ACTINOMYCETES AS A SOURCE OF "FARMER'S LUNG HAY" ANTIGEN.农民肺。嗜热放线菌作为“农民肺干草”抗原的来源。
Lancet. 1963 Sep 21;2(7308):607-11. doi: 10.1016/s0140-6736(63)90398-2.
4
Serologic studies in farmer's lung. Precipitins to the thermophilic actinomycetes.
Am Rev Respir Dis. 1974 Apr;109(4):464-8. doi: 10.1164/arrd.1974.109.4.464.
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Immunologic studies in hypersensitivity pneumonitis--quantitative precipitins and complement-fixing antibodies in symptomatic and asymptomatic pigeon breeders.
J Lab Clin Med. 1975 Apr;85(4):540-5.

使用一株血清学上不同的普通嗜热放线菌菌株诊断农民肺疾病。

Use of a serologically distinct strain of Thermoactinomyces vulgaris in the diagnosis of farmer's lung disease.

作者信息

Greatorex F B, Pether J V

出版信息

J Clin Pathol. 1975 Dec;28(12):1000-2. doi: 10.1136/jcp.28.12.1000.

DOI:10.1136/jcp.28.12.1000
PMID:1206112
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC475923/
Abstract

During investigations into farmer's lung disease it was noticed that Micropolyspora faeni (MF) was isolated and identified with ease, but difficulty was encountered in the identification of Thermoactinomyces vulgaris (TV), although an organism resembling TV was frequently isolated. Extracts prepared from the isolates resembling TV (called Thermoactinomyces vulgaris variant, TVV) when tested against the standard TV antiserum by double diffusion, did not produce any precipitin lines. When TVV extracts were tested against the serum of a patient from whom TVV had been isolated from the sputum, +++ precipitin lines were observed. With the TVV extracts the authors have demonstrated the existence of a serologically distinct strain of TV, and also that it would be a useful addition to the routine testing of antibodies to farmer's lung disease.

摘要

在对农民肺疾病的调查过程中，人们注意到，很容易分离并鉴定出嗜热放线多孢菌（MF），但在鉴定普通嗜热放线菌（TV）时却遇到了困难，尽管经常分离出一种类似TV的微生物。用双扩散法对从类似TV的分离物（称为普通嗜热放线菌变种，TVV）制备的提取物与标准TV抗血清进行检测时，未产生任何沉淀线。当用TVV提取物对一名痰中分离出TVV的患者血清进行检测时，观察到了 +++ 沉淀线。作者利用TVV提取物证明了存在一种血清学上不同的TV菌株，并且还证明它将有助于农民肺疾病抗体的常规检测。