Knazeje M, Belicová M, Kerný J, Mokán M
I. interná klinika MFN, Martin, Slovenská republika.
Vnitr Lek. 2002 May;48(5):416-21.
The authors discuss in the submitted review the problem of therapeutic use of beta-blockers in the treatment of cardiac failure. n the introduction they emphasize the medical and societal consequences of this disease with emphasis on necessary prevention. In the subsequent part they present a review of the most important clinical studies (completed and under way) focused on the mentioned problem. In the discussion they analyze the role of the sympathetic nervous system in the pathogenesis of cardiac failure and the theoretical basis of the use of beta-blockers in its treatment. In the conclusion they present a summary of practical principles for the use of beta-blockers in this indication.
作者在提交的综述中讨论了β受体阻滞剂在心力衰竭治疗中的治疗应用问题。在引言中，他们强调了这种疾病的医学和社会后果，并着重指出了必要的预防措施。在随后的部分中，他们对针对上述问题的最重要的临床研究（已完成的和正在进行的）进行了综述。在讨论中，他们分析了交感神经系统在心力衰竭发病机制中的作用以及使用β受体阻滞剂治疗心力衰竭的理论基础。在结论中，他们总结了在该适应症中使用β受体阻滞剂的实用原则。
