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氨基糖苷类药物使用情况的审计。

Audit of aminoglycosides usage.

作者信息

Ramesh M, John Siby, Narayanappa D

机构信息

Department of Pharmacy Practice, JSS College of Pharmacy, Mysore, India.

出版信息

Indian J Pediatr. 2002 May;69(5):385-8. doi: 10.1007/BF02722623.

DOI:10.1007/BF02722623
PMID:12061669
Abstract

OBJECTIVE

This study was aimed to evaluate the usage patterns of aminoglycosides in pediatric patients for their appropriateness.

METHODS

A retrospective review was conducted over a period of six months at J.S.S. Hospital, Mysore. Patients who received parenteral aminoglycosides and below the age of 12 years were included in this study.

RESULTS

A total of 197 pediatric patients were evaluated for the appropriateness and was found to be 72%, 86%, 85%, 43% & 53% for indication, dose, duration, safety and cost effectiveness respectively. Majority of the patients were treated with gentamicin (53%). The most frequent indication was respiratory tract infections (50%).

CONCLUSION

Effort was made to encourage judicious and quality use of aminoglycosides among the pediatricians of J.S.S. Hospital to ensure better patient care by implementation of the aminoglycosides guidelines.

摘要

目的

本研究旨在评估儿科患者氨基糖苷类药物的使用模式是否恰当。

方法

在迈索尔的J.S.S.医院进行了为期六个月的回顾性研究。本研究纳入了接受胃肠外氨基糖苷类药物治疗且年龄在12岁以下的患者。

结果

共对197名儿科患者的用药恰当性进行了评估,结果显示在适应证、剂量、疗程、安全性和成本效益方面的恰当率分别为72%、86%、85%、43%和53%。大多数患者接受庆大霉素治疗(53%)。最常见的适应证是呼吸道感染(50%)。

结论

通过实施氨基糖苷类药物指南,努力鼓励J.S.S.医院的儿科医生合理、优质地使用氨基糖苷类药物,以确保为患者提供更好的护理。

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本文引用的文献

1
Drug usage evaluation of aminoglycoside-induced nephrotoxicity in a community hospital.社区医院中氨基糖苷类药物所致肾毒性的用药评估
Hosp Formul. 1990 Oct;25(10):1092-4, 1096.
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Practical strategies for the appropriate use of antimicrobials.合理使用抗菌药物的实用策略。
Pharm World Sci. 1995 Jul 28;17(4):96-102. doi: 10.1007/BF01872385.
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Prospective audit of aminoglycoside usage in a general hospital with assessments of clinical processes and adverse clinical outcomes.对一家综合医院氨基糖苷类药物使用情况进行前瞻性审计,并对临床过程和不良临床结果进行评估。
Med J Aust. 1989 Aug 21;151(4):224-32. doi: 10.5694/j.1326-5377.1989.tb115996.x.
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A prospective study of long-term use of amikacin in a paediatrics department. Indications, administration, side-effects, bacterial isolates and resistance.儿科长期使用阿米卡星的前瞻性研究。适应证、用法、副作用、细菌分离株及耐药性。
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Commentary: An appraisal of tobramycin usage in pediatrics.评论:儿科妥布霉素使用情况评估
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