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吸烟、饮酒及抑郁对头颈癌患者生活质量的影响。

Effect of smoking, alcohol, and depression on the quality of life of head and neck cancer patients.

作者信息

Duffy Sonia A, Terrell Jeffrey E, Valenstein Marcia, Ronis David L, Copeland Laurel A, Connors Mary

机构信息

Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.

出版信息

Gen Hosp Psychiatry. 2002 May-Jun;24(3):140-7. doi: 10.1016/s0163-8343(02)00180-9.

DOI:10.1016/s0163-8343(02)00180-9
PMID:12062138
Abstract

This pilot study examined the relationship between smoking, alcohol intake, depressive symptoms and quality of life (QoL) in head and neck cancer patients. A questionnaire on smoking, alcohol, depressive symptoms and QoL was distributed to head and neck cancer patients (N=81). Over one-third (35%) of the respondents had smoked within the last 6 months, 46% had drunk alcohol within the last 6 months and 44% screened positive for significant depressive symptoms. About one-third (32%) of smokers were interested in smoking cessation services and 37% of patients with depressive symptoms were interested in depression services. However, only 9% of those who drank alcohol expressed interest in alcohol services. Smoking was negatively associated with five scales of the SF-36V including Physical Functioning, General Health, Vitality, Social Functioning, and Role-Emotional Health. Depressive symptoms were negatively associated with all eight scales on the SF-36V and all four scales of the Head and Neck Quality of Life instrument. Surprisingly, alcohol was not found to be associated with any of the QoL scales. While smoking, alcohol intake and depression may be episodically treated, standardized protocols and aggressive intervention strategies for systematically addressing these highly prevalent disorders are needed in this population.

摘要

这项初步研究调查了头颈癌患者吸烟、饮酒、抑郁症状与生活质量(QoL)之间的关系。向头颈癌患者(N = 81)发放了一份关于吸烟、饮酒、抑郁症状和生活质量的问卷。超过三分之一(35%)的受访者在过去6个月内吸烟,46%在过去6个月内饮酒,44%的人筛查出有明显的抑郁症状呈阳性。约三分之一(32%)的吸烟者对戒烟服务感兴趣,37%有抑郁症状的患者对抑郁症服务感兴趣。然而,只有9%饮酒者对戒酒服务表示感兴趣。吸烟与SF - 36V的五个量表呈负相关,包括身体功能、总体健康、活力、社会功能和角色情感健康。抑郁症状与SF - 36V的所有八个量表以及头颈生活质量工具的所有四个量表呈负相关。令人惊讶的是,未发现饮酒与任何生活质量量表相关。虽然吸烟、饮酒和抑郁可能会得到间歇性治疗,但该人群需要标准化方案和积极的干预策略来系统解决这些高度普遍的疾病。

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