Department of Otolaryngology-Head and Neck Surgery, University of Iowa College of Medicine, Iowa City, Iowa, USA.
Head Neck. 2010 Jul;32(7):905-12. doi: 10.1002/hed.21281.
The effect of posttreatment alcohol consumption on health-related quality of life (QOL) and factors predicting overall QOL and continued alcohol consumption were examined in patients with head and neck cancer.
Self-reported alcohol use and abuse 1 year after diagnosis was analyzed.
Although current drinkers (44.5% of 283 patients) had better overall QOL and fewer depressive symptoms, current social drinkers had the best scores, whereas current problem drinkers had the worst. Female sex, fewer depressive symptoms, less pain, and better eating function predicted better QOL. Oral function was the only predictor of 12-month alcohol use.
Depression, pain, and eating function predicted overall QOL. Alcohol consumption was not associated with QOL, but was associated with better oral function, which in turn predicted better QOL. Alcohol consumption itself does not improve QOL in this population, and these patients should be counseled regarding detrimental effects of continued drinking after treatment.
本研究旨在探讨治疗后饮酒对健康相关生活质量（QOL）的影响，以及对头颈部癌症患者整体 QOL 和持续饮酒的预测因素。
分析了患者诊断后 1 年的自我报告饮酒和滥用情况。
尽管目前饮酒者（283 例患者中的 44.5%）的整体 QOL 和抑郁症状较少，但目前社交饮酒者的评分最高，而目前有问题的饮酒者评分最低。女性、较少的抑郁症状、较少的疼痛和更好的进食功能预示着更好的 QOL。口腔功能是 12 个月饮酒的唯一预测因素。
抑郁、疼痛和进食功能预测整体 QOL。饮酒与 QOL 无关，但与更好的口腔功能相关，而口腔功能又预测更好的 QOL。在这一人群中，饮酒本身并不能提高 QOL，因此应告知这些患者在治疗后继续饮酒的有害影响。
