Klepper L Ia
Med Tekh. 2002 Mar-Apr(2):31-7.
A method of approximate calculation of the probability of resorption of a lesion focus by means of three mathematical models: the Poisson model, the Klepper model, and the LQ-model (the PKLQ method) is described. The method is based on a procedure for reducing SOD to the preset scope of a lesion focus. It is suggested that radio-sensitive (RS) cells predominate in the focus of lesion; radio-resistant cells are available in small quantities or their radiobiological properties differ from RS cells.
描述了一种通过三种数学模型(泊松模型、克莱珀模型和LQ模型,即PKLQ方法)近似计算病变灶吸收概率的方法。该方法基于将超氧化物歧化酶(SOD)降低到病变灶预设范围的程序。研究表明,病变灶中放射敏感(RS)细胞占主导;放射抗性细胞数量较少,或者其放射生物学特性与RS细胞不同。