Ito Isao, Ishida Tadashi, Hashimoto Toru, Arita Machiko, Osawa Makoto, Mishima Michiaki, Nonoyama Shigeaki
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Japan.
Scand J Infect Dis. 2002;34(4):305-7. doi: 10.1080/00365540110080151.
A 33-y-old man with Hyper-IgM syndrome developed a severe tuberculous disease complicated by pleuritis and spondylitis. An abnormally decreased CD4/CD8 ratio, decreased CD4 + T-cell count and depressed natural killer cell activity implicated a coexistent cell-mediated immunodeficiency. To our knowledge, this is the first detailed report of tuberculosis associated with Hyper-IgM syndrome.
一名患有高IgM综合征的33岁男性患上了严重的结核病，并伴有胸膜炎和脊柱炎。异常降低的CD4/CD8比值、减少的CD4 + T细胞计数以及低下的自然杀伤细胞活性提示存在细胞介导的免疫缺陷。据我们所知，这是首例关于高IgM综合征合并结核病的详细报告。
