Blackwell Sean C, Abundis Margot G, Nehra Paul C
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI, USA.
Am J Obstet Gynecol. 2002 Jun;186(6):1130-2. doi: 10.1067/mob.2002.122987.
The purpose of this study was to determine the pregnancy loss rate after genetic amniocentesis that was performed by general obstetrician-gynecologists in a community hospital.
Medical records and billing information were used to identify all genetic amniocenteses that had been performed by a group of general obstetricians-gynecologists from 1996 through 2000. Maternal charts were reviewed for data that were pertinent to the risk of fetal loss: maternal age, parity, ethnicity, procedure indication, gestational age at procedure, karyotype results, physician operator, gestational age at delivery, and live birth/stillbirth.
During this 5-year time period, 370 procedures were performed by this physician group. Completed delivery outcomes were available on 369 of 370 patients (99.7%). Three patients underwent pregnancy termination. Data were analyzed on the remaining 366 patients. There was 1 pregnancy loss (amniocentesis at 17 weeks with vaginal bleeding at 21 week and preterm delivery at 24 weeks). There was 1 other procedure-related complication: membrane rupture 7 days after the procedure, with spontaneous resealing of the membranes after prolonged bedrest.
Over a 5-year period, pregnancy loss after midtrimester amniocentesis performed by general obstetrician-gynecologists was 1 in 366 procedures.
本研究旨在确定社区医院普通妇产科医生进行遗传羊膜穿刺术后的流产率。
利用病历和计费信息，识别1996年至2000年一组普通妇产科医生所进行的所有遗传羊膜穿刺术。查阅产妇病历，获取与胎儿丢失风险相关的数据：产妇年龄、产次、种族、手术指征、手术时的孕周、核型结果、手术医生、分娩时的孕周以及活产/死产情况。
在这5年期间，该医生团队共进行了370例手术。370例患者中有369例（99.7%）获得了完整的分娩结局。3例患者终止了妊娠。对其余366例患者的数据进行了分析。有1例流产（17周时进行羊膜穿刺术，21周时出现阴道出血，24周时早产）。还有1例与手术相关的并发症：术后7天胎膜破裂，长时间卧床休息后胎膜自行愈合。
在5年期间，普通妇产科医生在孕中期进行羊膜穿刺术后的流产率为366例手术中有1例。
