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妊娠合并急性胰腺炎时的急性肾功能不全

[Acute renal insufficiency during pregnancy with acute pancreatitis].

作者信息

Nikolov A, Dimitrov A, Liubomirova M, Stoĭkova V, Dzherasi R

出版信息

Akush Ginekol (Sofiia). 2002;41(2):49-52.

Abstract

According to current data the incidence of acute pancreatitis is from 1:1000 to 1:5000. Symptoms vary a lot, one of rare but most severe complications being acute renal failure. The case is a 24-year-old pregnant patients--30-th gestational week with symptoms of acute pancreatitis based most probably on hereditary hypertriglyceridemia and hypercholesterolemia. Parallel to acute inflammation of pancrease a hypercoagulation syndrome developed. It is possible that acute renal failure was caused by active thrombus formation. Because of danger for the life of mother and baby, an urgency preterm Cesarean Section was performed. Resussitation post-surgery care and drug therapy (lowmolecular anticoagulants, antibiotics, spasmolytics and analgetics, protease--inhibitors, inhibitors of protome pump, regulators and inhibitors of pancreas secretion normalize renal and pancreatic function if based on special dietary regimr. Coagulation status also normalizes.

摘要

根据目前的数据,急性胰腺炎的发病率为1:1000至1:5000。症状差异很大,其中一种罕见但最严重的并发症是急性肾衰竭。该病例是一名24岁的孕妇,孕30周,患有急性胰腺炎症状,最有可能是基于遗传性高甘油三酯血症和高胆固醇血症。在胰腺急性炎症的同时,出现了高凝综合征。急性肾衰竭可能是由活跃的血栓形成引起的。由于对母婴生命构成危险,进行了紧急早产剖宫产。术后复苏护理和药物治疗(低分子抗凝剂、抗生素、解痉药和镇痛药、蛋白酶抑制剂、质子泵抑制剂、胰腺分泌调节剂和抑制剂),如果基于特殊饮食方案,可使肾功能和胰腺功能正常化。凝血状态也会恢复正常。

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