Baráth P, Strausz I, Kékes E, Szántó A
Acta Physiol Acad Sci Hung. 1979;53(3):311-22.
The regional decrease of the speed and extent of the contraction and the relaxation of the canine myocardium induced by coronary ligation was enhanced by intravenously administered nitroglycerin (GTN), simultaneously with the decrease of the left ventricular pressure, while the increase of myocardial fiber length caused by that procedure was partly abolished. The above changes could be reproduced by GTN applied directly onto the ischaemic myocardial surface even before the decrease of the left ventricular pressure. These changes induced by GTN might play a role in the decrease or abolishment of regional asynergic wall motion.
静脉注射硝酸甘油（GTN）可增强冠状动脉结扎所致犬心肌收缩和舒张速度及范围的局部降低，同时左心室压力降低，而该操作引起的心肌纤维长度增加则部分被消除。甚至在左心室压力降低之前，直接将GTN应用于缺血心肌表面也可重现上述变化。GTN引起的这些变化可能在局部不协调壁运动的减少或消除中起作用。
