Hwang Ildoo, Chen Huei-Chi, Sheen Jen
Department of Genetics, Harvard Medical School, Boston, MA 02114, USA.
Plant Physiol. 2002 Jun;129(2):500-15. doi: 10.1104/pp.005504.
The two-component system, consisting of a histidine (His) protein kinase that senses a signal input and a response regulator that mediates the output, is an ancient and evolutionarily conserved signaling mechanism in prokaryotes and eukaryotes. The identification of 54 His protein kinases, His-containing phosphotransfer proteins, response regulators, and related proteins in Arabidopsis suggests an important role of two-component phosphorelay in plant signal transduction. Recent studies indicate that two-component elements are involved in plant hormone, stress, and light signaling. In this review, we present a genome analysis of the Arabidopsis two-component elements and summarize the major advances in our understanding of Arabidopsis two-component signaling.
双组分系统由感知信号输入的组氨酸(His)蛋白激酶和介导输出的响应调节因子组成,是原核生物和真核生物中一种古老且进化保守的信号传导机制。在拟南芥中鉴定出54种组氨酸蛋白激酶、含组氨酸的磷酸转移蛋白、响应调节因子及相关蛋白,这表明双组分磷酸化信号传递在植物信号转导中具有重要作用。最近的研究表明,双组分元件参与植物激素、胁迫和光信号传导。在本综述中,我们对拟南芥双组分元件进行了基因组分析,并总结了我们对拟南芥双组分信号传导理解方面的主要进展。