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卵巢浆液性囊腺癌肝转移瘤的肝切除术

Hepatic resection of metastatic tumor from serous cystadenocarcinoma of the ovary.

作者信息

Lee Jong Hoon, Kim Kyung Sik, Chung Cheol Woon, Park Young Nyun, Kim Byong Ro

机构信息

Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.

出版信息

J Korean Med Sci. 2002 Jun;17(3):415-8. doi: 10.3346/jkms.2002.17.3.415.

Abstract

Metastatic carcinomas are the largest group of malignant tumors of the liver. But parenchymal liver metastasis from cystic ovarian adenocarcinoma is very rare. We report a case in which the resection of metastatic liver neoplasm from ovarian serous cystadenocarcinoma was done 7 yr after initial treatment. A 48-yr-old oriental housewife complained of easy fatigability and right lower quadrant discomfort. The hepatic mass was detected by ultrasonographic examination. Serum albumin, bilirubin, and aspartate aminotransferase/alanine aminotransferase were normal. Alkaline phosphatase level was slightly increased at 146 IU/L. A tumor marker study showed alpha-fetoprotein 0.97 IU/mL, carcinoembryonic antigen 0.965 ng/mL, cancer antigen 125 1,267 ng/mL and CA 19-9 106.1 ng/mL. The operation involved cholecystectomy and segmentectomy VI and VII of the liver. The patient recovered from the surgery without any complication. On the 10th postoperative day, the patient received a single-regimen chemotherapy with paclitaxel (Taxol, 155 mg/m(2) BSA) and was discharged. She has been carefully followed-up without any evidence of recurrence after completion of the remaining 5 cycles of chemo-therapy, at intervals of three weeks.

摘要

转移性癌是肝脏恶性肿瘤中最大的一组。但卵巢囊性腺癌的肝实质转移非常罕见。我们报告一例在初始治疗7年后切除卵巢浆液性囊腺癌肝转移瘤的病例。一名48岁的东方家庭主妇主诉易疲劳和右下腹不适。通过超声检查发现肝脏肿块。血清白蛋白、胆红素和天冬氨酸转氨酶/丙氨酸转氨酶均正常。碱性磷酸酶水平略有升高,为146 IU/L。肿瘤标志物检查显示甲胎蛋白0.97 IU/mL、癌胚抗原0.965 ng/mL、癌抗原125 1267 ng/mL和CA 19-9 106.1 ng/mL。手术包括胆囊切除术和肝脏Ⅵ段和Ⅶ段切除术。患者术后恢复良好,无任何并发症。术后第10天,患者接受了紫杉醇(泰素,155 mg/m²体表面积)单药化疗,随后出院。在完成其余5个周期(每三周一次)的化疗后,对她进行了仔细随访,未发现任何复发迹象。

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