Lee Jong Hoon, Kim Kyung Sik, Chung Cheol Woon, Park Young Nyun, Kim Byong Ro
Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
J Korean Med Sci. 2002 Jun;17(3):415-8. doi: 10.3346/jkms.2002.17.3.415.
Metastatic carcinomas are the largest group of malignant tumors of the liver. But parenchymal liver metastasis from cystic ovarian adenocarcinoma is very rare. We report a case in which the resection of metastatic liver neoplasm from ovarian serous cystadenocarcinoma was done 7 yr after initial treatment. A 48-yr-old oriental housewife complained of easy fatigability and right lower quadrant discomfort. The hepatic mass was detected by ultrasonographic examination. Serum albumin, bilirubin, and aspartate aminotransferase/alanine aminotransferase were normal. Alkaline phosphatase level was slightly increased at 146 IU/L. A tumor marker study showed alpha-fetoprotein 0.97 IU/mL, carcinoembryonic antigen 0.965 ng/mL, cancer antigen 125 1,267 ng/mL and CA 19-9 106.1 ng/mL. The operation involved cholecystectomy and segmentectomy VI and VII of the liver. The patient recovered from the surgery without any complication. On the 10th postoperative day, the patient received a single-regimen chemotherapy with paclitaxel (Taxol, 155 mg/m(2) BSA) and was discharged. She has been carefully followed-up without any evidence of recurrence after completion of the remaining 5 cycles of chemo-therapy, at intervals of three weeks.
转移性癌是肝脏恶性肿瘤中最大的一组。但卵巢囊性腺癌的肝实质转移非常罕见。我们报告一例在初始治疗7年后切除卵巢浆液性囊腺癌肝转移瘤的病例。一名48岁的东方家庭主妇主诉易疲劳和右下腹不适。通过超声检查发现肝脏肿块。血清白蛋白、胆红素和天冬氨酸转氨酶/丙氨酸转氨酶均正常。碱性磷酸酶水平略有升高,为146 IU/L。肿瘤标志物检查显示甲胎蛋白0.97 IU/mL、癌胚抗原0.965 ng/mL、癌抗原125 1267 ng/mL和CA 19-9 106.1 ng/mL。手术包括胆囊切除术和肝脏Ⅵ段和Ⅶ段切除术。患者术后恢复良好,无任何并发症。术后第10天,患者接受了紫杉醇(泰素,155 mg/m²体表面积)单药化疗,随后出院。在完成其余5个周期(每三周一次)的化疗后,对她进行了仔细随访,未发现任何复发迹象。